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Goes to work in minutes. Contains a powerful ingredient, simethicone, the anti-gas medicine recommended most by physicians and pharmacists for relief of gas. 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It provides the same complete protection from frequent heartburn in easy-to-swallow tablets. Nexium 24HR tablets work by blocking acid directly at the source, giving you 24 hours of protection from frequent heartburn. Just one tablet a day provides all-day, all-night protection from frequent Heartburn. Nexium 24HR is the #1 Selling OTC frequent heartburn brand. It’s possible while taking Nexium 24HR. Use as directed for 14 days to treat frequent heartburn. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. 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